Special Report, Health, Americas

[AprpdlNuh]

A similar trial in South Africa, where a new, more contagious variant is dominant, produced similar results. Researchers found the Johnson & Johnson vaccine to be slightly less effective at preventing all illness there - 64 percent overall - but was still 82 percent effective at preventing severe disease. The FDA report also indicates that the vaccine protects against other variants from Britain and Brazil, too. How Is It Different From the Moderna and Pfizer Vaccines? The most basic difference is that the Johnson & Johnson vaccine is an adenovirus vector vaccine, while the Moderna and Pfizer vaccines are both mRNA vaccines. Messenger RNA vaccines use genetic instructions from the coronavirus to tell a person's cells to make the spike protein, but these don't use another virus as a vector. There are many practical differences, too. Both of the mRNA-based vaccines require two shots. The Johnson & Johnson vaccine requires only a single dose. This is key when vaccines are in short supply.




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